Sep 2026
Stepwise neutrophil-to-neuron targeting nanotherapy for mitochondrial protection and blood-brain barrier preservation in ischemic stroke.
A dual-modal, stepwise-targeting lipid nanoparticle platform that integrates mitochondrial protection with matrix metalloproteinase-12 (MMP-12) silencing to achieve coordinated neurovascular protection in ischemic stroke is reported.
Xu-Rui Gu, Sai Wang, Lei Chen et al.
· Journal of Controlled Releas... · 0 citations