Author

Hang Xu

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Open access Oct 2026

A Knowledge Graph Framework for Longitudinal Congenital Heart Disease Modeling: Methodology Corner.

BACKGROUND Congenital heart disease (CHD) is characterized by evolving clinical trajectories; staged interventions; and complex relationships among diagnoses, procedures, and encounters. Conventional machine learning applied to electronic health record (EHR) data often rely on static feature representations that do not...

Hang Xu, Lila Cunge, Zhengyang Ming et al. · JACC: Advances · 0 citations

Open access Oct 2026

Prospective evaluation of donor-derived cell-free DNA for noninvasive detection of acute rejection in an Asian heart transplant population

Endomyocardial biopsy (EMB) is the gold standard for diagnosing post-heart transplant acute rejection (AR) but is invasive. Donor-derived cell-free DNA (dd-cfDNA) is a promising noninvasive biomarker, yet thresholds for Asian recipients remain undefined. This prospective study enrolled 80 patients, with 299 dd-cfDNA sp...

Shan-Shan Zheng, Sheng Liu, Zhi-Yuan Zhu et al. · Transplant International · 0 citations