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Author

Hang Yuan

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Open access Sep 2026

Screening of known gut microbiome-derived metabolites in anti-tumor immunity of colorectal cancer

Abstract Background Most colorectal cancers (CRCs) patients with microsatellite stability (MSS) have minimal benefit from immune checkpoint inhibitor monotherapy, and even after PD-1/PD-L1 blockade, T cell function remains inadequately restored, highlighting the importance of PD-1 downstream signaling events. SHP-2 is...

Xi-Nan Zhang, Zi-Xuan Li, Hui Hua et al. · 0 citations
Open access Sep 2026

Let-7c-3p Suppresses Ovarian Cancer Progression by Targeting S100A6 and Inhibiting JAK-STAT Signaling

It is shown that S100A6 is present at elevated levels in ovarian cancer and promotes cancer cell proliferation, migration, and invasion while suppressing cell death, and a small regulatory RNA molecule, Let-7c-3p, that directly suppresses S100A6 production is identified.

Bin-Liang Yuan, Xiao-Yan Huang, Juan Li et al. · 0 citations

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