Author

Hannah J. Lucas-Clarke

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Open access Oct 2026

Alzheimer’s disease risk gene Wwox controls amyloid pathology through metabolic reprogramming

Findings identify WWOX as a regulator of neuronal metabolic state, linking genetic risk to amyloid pathology via metabolic reprogramming, and highlight WWOX activation as a potential therapeutic strategy in Alzheimer’s disease.

Hannah J. Lucas-Clarke, D. Maddison, L. Amadio et al. · Brain Communications · 0 citations