Hans J. C. T. Wessels

Proteome modulation by opposite inotropic drugs in human engineered cardiac tissue revealed by topology-driven cross-modal integration

Engineered heart tissues (EHTs) represent an innovative platform enabling physiologically relevant in vitro evaluation of drug-induced cardiac responses. While functional characterization remains central to EHTs, molecular profiling is increasingly used to elucidate mechanisms underlying drug-induced phenotypes. Proteo...