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Author

Hany M. Elsheikha

3 papers indexed here

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Open access Sep 2026

Farming reshapes the gut resistome, virulome, and mobilome of Cervidae

ABSTRACT The rapid expansion of cervid farming raises concerns about antimicrobial resistance (AMR) dissemination, yet its impact on the Cervidae gut microbiome remains poorly characterized. We integrated 89 newly sequenced fecal metagenomes with 599 publicly available datasets, comprising 285 metagenomes from farmed c...

Yu-Zhe Sun, Jin-Wen Su, Hany M. Elsheikha et al. · 1 citation
Sep 2026

Interkingdom remodeling of the intestinal bacteriome and virome during Toxoplasma gondii infection in rats.

Toxoplasma gondii infection is associated with intestinal microbiome disruption, but its effects on genome-resolved bacterial populations, the gut virome, and bacteriome-virome relationships remain poorly understood. Using previously generated shotgun metagenomic datasets from 36 intestinal samples collected from 18 Sp...

Meng-Ting Yang, Ting Bai, Ji-Xin Zhao et al. · 0 citations
Aug 2026

Untargeted metabolomics reveals L-Lysine depletion as a host-directed therapeutic target in Toxoplasma gondii infection.

Toxoplasmosis is a widespread zoonotic disease causing severe outcomes in immunocompromised individuals and during pregnancy. Current therapeutic options target actively replicating stages of the parasite and show limited efficacy against chronic infection. While research has focused on parasite-directed therapies, hos...

Xue-Yao Wang, Ji-Xin Zhao, Xiao-Tong Chen et al. · 1 citation

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