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Author

Hao-Bin Hou

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Open access Oct 2026

Integrated bioinformatics and machine learning identify key hub genes in early-onset gastric cancer

Early-onset gastric cancer (EOGC) represents a clinically and biologically distinct subtype of gastric cancer characterized by unique molecular features. However, its underlying molecular mechanisms remain unclear. This study aimed to identify EOGC-associated hub genes using an integrated bioinformatics and machine...

Shao-Xiong Yi, Qiu-Xia Chen, Jia-Xin Wu et al. · 0 citations
Open access Sep 2026

Establishment and characterization of patient-derived mucinous gastric cancer organoids with faithful histopathological features and reproducible drug response patterns

Background Mucinous gastric cancer (MGC) is a rare subtype of gastric cancer (GC) characterized by distinct histological features and clinical behavior. However, the lack of specific in vitro models for MGC has hindered progress in understanding its carcinogenic mechanisms and developing effective therapeutic strategie...

Hao-Bin Hou, Su-Fen Fang, Wei R. Chen et al. · 0 citations

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