PopPert: Population-level Joint-Distribution Modeling for Single-Cell Perturbation Prediction
PopPert predicts perturbation-induced changes in distribution parameters, eliminating the need for cell-level correspondence and reducing sensitivity to single-cell noise, establishing population-level joint distribution learning as an effective paradigm for predicting transcriptional responses from unpaired single-cel...
Han-Dong Wang, Jiaxin Qi, Hao-Chen Feng et al.
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