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Hao-Dong Yang

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Open access Sep 2026

A bis(benzimidazolyl)-based anion transporter triggers chloride-initiated pyroptosis of MDA-MB-468 and 4T1 triple-negative breast cancer cells in vitro and in vivo.

As a highly heterogeneous subtype of breast cancers, triple-negative breast cancer (TNBC) poses significant therapeutic challenges. This study aims to systematically investigate the activity and mechanism of action of a benzimidazole-based anion transporter (i.e., compound 1) in treating TNBC both in vivo and in vitro....

Li Chen, Hao-Dong Yang, Jin-Hui Hu et al. · 0 citations

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