CellMAGE: cell-type deconvolution for multi-parent population analysis of gene expression
Single-cell RNA-sequencing remains prohibitively expensive for multiparental population (MPP) studies. Existing deconvolution methods treat bulk RNA-seq as genetically anonymous mixtures, but in MPPs, the proportional contribution of each parental strain to each progeny’s transcriptome is already known. CellMAGE (Cell-...