Oct 2026
A synthetic cationic thiopyrylium compound exploits preferential phosphatidylserine recognition to exert antifungal activity.
Invasive candidiasis poses a severe global health threat, with limited antifungal options and escalating drug resistance demanding novel therapeutic strategies. Here, we report IMB-G3, a cationic thiopyrylium-styryl compound, as a broad-spectrum antifungal agent that preferentially targets phosphatidylserine. IMB-G3 ex...
Bing-Chen Li, Jing Zhang, Shu-Yi Si et al.
· Bioorganic chemistry (Print) · 0 citations