Gestational prednisone exposure causes subfertility in male offspring mice: Role of testicular E2f1 N6-methyladenosine modification.
Previous studies showed that abnormally high glucocorticoid exposure during pregnancy impaired fetal development and health. However, its impacts on fertility in adult male offspring and the underlying mechanisms remain unknown. Here, pregnant mice were treated intragastrically with prednisone (PDN), a widely used synt...