An Integrated Cascade-Amplified Microfluidic Biosensor for Reconfigurable Profiling of CRC-Associated Faecal Extracellular Vesicle Surface Proteins.
Faecal extracellular vesicles (EVs) provide disease-relevant molecular information for non-invasive colorectal cancer (CRC) analysis. However, sensitive EV surface protein profiling remains challenging because low-abundance targets are obscured by heterogeneous vesicles and complex matrices. Here, an integrated cascade...