Author

Hao Peng

2 papers indexed here

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Oct 2026

Neferine Exerts a Protective Effect on Rat Osteoarthritis by Upregulating Autophagy.

Osteoarthritis (OA) is a prevalent chronic joints disorder, characterized by progressive degeneration of articular cartilage accompanied by joint inflammation. The development of a safe and effective pharmacological therapy is highly anticipated. This research was designed to comprehensively investigate the function of...

Han-Zhe Xu, Wen-Xiang Cai, Heng-Te Xing et al. · The FASEB Journal · 0 citations

Open access Aug 2026

Procyanidin C1 activates Nrf2/HO-1 to preserve in vivo mitochondrial homeostasis and counter chondrocyte senescence in osteoarthritis

Findings establish a mechanistic link between PCC1, Nrf2/HO-1 activation and chondrocyte mitochondrial homoeostasis in osteoarthritis, and support Nrf2-directed senotherapies as a regenerative strategy to slow OA progression.

Yubiao Zhang, Mao Chen, Wenxiang Cai et al. · Cell Death & Disease · 1 citation