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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Hao Song

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Open access Sep 2026

Targeting ZMYND8 unleashes IL-2 signalling to override T cell exhaustion.

CD8+ T cell exhaustion impedes control of chronic viral infection and cancer. This hypofunctional state is characterized by downregulation of the high-affinity IL-2 receptor (IL-2R) and STAT5 signalling, and differentiation from progenitor exhausted to terminally exhausted T cells rather than cytotoxic effector-like ce...

Yan Wang, Hao Shi, Nicole M. Chapman et al. · 0 citations

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