Open access
Aug 2026
Empagliflozin Reduces Post-Myocardial Infarction Inflammation via BDH1/β-Hydroxybutyrate-Mediated NF-κB Modulation in Macrophages and the Heart.
EMPA attenuates maladaptive inflammation and confers cardioprotection after MI, potentially through a BDH1/β-HB/NF-κB pathway in macrophages, and identifies a novel and potential pharmacological mechanism of SGLT2 inhibition in the context of post-MI inflammation.
Ji'e Yang, Ke Meng, Guo-Hong Wu et al.
· Journal of Cardiovascular Ph... · 0 citations