Author

Hao Yao

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Sep 2026

Discovery of Biaryl amide-containing transmembrane serine protease 2 (TMPRSS2) inhibitors for the treatment of prostate Cancer.

Results indicate that XDTM13 and XDTM14 are promising lead compounds for TMPRSS2 inhibition, with XDTM13 emerging as a particularly potent candidate for further development.

Zi-Jie Jin, Hao Yao, Jiang-Hui Ye et al. · Bioorganic chemistry (Print) · 0 citations