DNA Nanotube-Confined 3D Walker Enables Endogenous Dual-Activated AND Gate Imaging of Tumor-Associated piRNA
Intracellular molecular imaging for tumor biomarkers faces significant challenges in achieving high specificity and sensitivity, primarily due to signal leakage and the low abundance of target molecules. Herein, we develop an endogenous dual-activation sensing platform (termed E-DWRB) that integrates an AND logic gat...