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Author

Hao Zhang

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Open access Sep 2026

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

ABSTRACT Sepsis‐induced acute lung injury (ALI) is a lethal inflammatory condition with limited therapeutic options. Macrophage autophagic homeostasis is essential to constrain septic ALI inflammation, though its upstream regulation remains elusive. Here, we report that lysosomal‐associated protein transmembrane 5 (LAP...

Lang Jiang, Qi-Lan Li, Hao Liu et al. · 0 citations

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