Nanotechnology-Enabled Immunotherapy for Colorectal Cancer: Overcoming the “Cold” Tumor Microenvironment in Microsatellite-Stable Disease
Background Immune checkpoint inhibitors (ICIs) have transformed the management of mismatch repair-deficient/microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC), yet the ~95% of patients with mismatch repair-proficient/microsatellite-stable (pMMR/MSS) disease derive little benefit owing to an immunologi...