Author

Hao Zheng

2 papers indexed here

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Open access Sep 2026

SAMSN1 restricts Japanese encephalitis virus replication by recruiting TRIM21 to degrade viral proteins and activate the interferon pathway

Japanese encephalitis virus (JEV), a zoonotic mosquito-transmitted flavivirus, induces human encephalitis and swine reproductive diseases. No antiviral drugs or treatments exist for flavivirus infections, which cause severe symptoms. Even though some host proteins can suppress flavivirus proliferation, the virus can in...

Chen Wang, Wen-Zhen Qin, Xing-Ya Wang et al. · Veterinary Research · 0 citations

Aug 2026

A recombinant attenuated PRRSV vaccine expressing the PCV2 capsid protein confers protective immunity in pigs.

RHuN4-F112-Cap has potential as a bivalent live-vector vaccine candidate against PRRSV and PCV2, and vaccinated piglets showed reduced DNA loads and milder lymphoid lesions after PCV2 challenge, and reduced clinical signs, lower PRRSV RNA loads, milder pulmonary lesions, and improved survival after highly pathogenic PR...

Shuolei Gao, Jiecong Yan, Juan Wang et al. · Vaccine · 0 citations