Microfluidic Engineered Gelatin Methacryloyl Microsphere Scaffolds Loaded with Extracellular Vesicles Derived from Mesenchymal Stromal Cells Promote Functional Recovery in Rats with Spinal Cord Injury.
Spinal cord injury (SCI) leads to significant locomotor, sensory, and autonomic deficits and remains refractory to current therapies. Extracellular vesicles from mesenchymal stromal cells (MSC-EVs) are potential acellular therapeutic strategy for tissue regeneration, but rapid clearance and poor lesion retention limit...