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Author

Harikesh Kumar Gupta

2 papers indexed here

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Sep 2026

Rational design, synthesis, and biological evaluation of indole-piperazine based α-ketoamide derivatives as dual Aβ and tau aggregation modulators for Alzheimer's disease.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by pathological aggregation of amyloid-β (Aβ) and tau proteins, representing two major hallmarks of disease progression. Targeting both aggregation pathways simultaneously offers a promising therapeutic strategy. Building upon our previo...

Bhanuranjan Das, Anurag T. K. Baidya, Deepak Chouhan et al. · 0 citations
Aug 2026

Designed NIR-I Emissive and Selective G-Quadruplex DNA Binder with Altered Organelle Specificity.

In this work, we report the discovery of a G-quadruplex DNA-selective and near-infrared (NIR-I) emissive G-quadruplex binder derived from a known styryl-quinolinium-based compound. This molecule is unique in its class, with an emission wavelength above 800 nm, and displays selective G-quadruplex binding. Among the synt...

Sachin Metangle, Harikesh Kumar Gupta, Nabanita Das et al. · 0 citations

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