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Author

Harrison B. Cullen

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2 papers indexed here

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Open access Sep 2026

An iron-regulated methionine redox axis governs adipose browning and cancer cachexia.

Adipose browning and atrophy are early events of cachexia, a lethal metabolic disorder affecting nearly half of the population with cancer. Here, using individual-derived specimens and mouse models, we identified an iron-dependent pathway that initiates adipose browning in both physiological and cachectic settings. Upo...

Jung Seung Nam, Sung Shin Ahn, Yeonoh Shin et al. · 1 citation
Review Aug 2026

Message in a Bottle: The Therapeutic Potential of Domesticated Capsid Proteins.

Host-encoded Gag CA proteins may offer complementary features such as lower immunogenicity, flexible cargo capacity, and tissue-specific targeting, and open questions remain regarding release and cellular entry mechanisms, in vivo tropism, determinants of immunogenicity across family members, and safety.

Harrison B. Cullen, Luke E. Berchowitz · 0 citations

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