Open access
Sep 2026
Rab11-exosome biogenesis regulators mediate Aβ-induced intercellular propagation of endolysosomal trafficking defects and neurodegeneration
Alzheimer’s Disease (AD) is characterised by two histopathological hallmarks, intracellular tau-containing neurofibrillary tangles and extracellular amyloid plaques containing β-amyloid (Aβ), a specific cleavage product of Amyloid Precursor Protein (APP). Initiation of Aβ-induced neuronal pathology, however, has been p...
A. Cording, Bhavna Verma, Adam Arous et al.
· bioRxiv · 0 citations