Open access
Aug 2026
Investigating the impact of trehalose crystallization on protein aggregation in lyophilized formulations
Trehalose is a commonly used lyoprotectant for stabilizing proteins in lyophilized formulations. Its physical state plays a critical role in maintaining both the physical and chemical stability of proteins. In this study, three types of protein/trehalose systems were studied to understand the impact of trehalose crysta...
Rachana Sapkota, Isabella Perez Mejia, Cole W. Tower et al.
· AAPS Open · 0 citations