Open access
Aug 2026
The bacterial pH gradient contributes to persistence in Mycobacterium tuberculosis
NC protected Mtb from lethal doses of most standard TB drugs, and showed that disruption of the pH gradient and consequent intracellular acidification is needed to induce tolerance, and that protection is tunable by external pH.
Hassan E. Eldesouky, Kristin N. Adams, Justin K Brache et al.
· mBio · 0 citations