Attenuation of Vascular Cognitive Impairment by Panaxadiol Through Promoting Hippocampal Angiogenesis in a Chronic Cerebral Hypoperfusion Model.
OBJECTIVE This study explores the therapeutic efficacy and mechanisms of panaxadiol (PD), a ginseng-derived sapogenin, in a mouse model of vascular cognitive impairmentinduced by chronic cerebral hypoperfusion (CCH). METHODS CCH was induced in C57BL/6 mice by bilateral common carotid artery stenosis (BCAS). Mice were...