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Author

Heather Tsong

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Open access Sep 2026

PP2A and CDK16 antagonistically regulate WIPI2B phosphorylation and neuronal autophagosome biogenesis

Summary Autophagy is a homeostatic mechanism for recycling cellular constituents. In primary murine neurons, autophagosome biogenesis declines during aging. Importantly, this decline can be restored by the ectopic expression of key autophagy component WIPI2B. The phosphorylation state of WIPI2B serine 395 is critical f...

Heather Tsong, M. Waxham, Andrea K. H. Stavoe · 1 citation

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