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Author

Heba R Alrefaey

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Open access Aug 2026

Methylglyoxal Attenuates Mycobacterium avium subspecies paratuberculosis (MAP)-Induced Pro-Inflammatory Macrophage Programming Associated with NRF-2 Antioxidant Responses and Reduced MCT4/Lactate-Linked Inflammatory Markers

It is suggested that hormetic concentration of MGO mitigates MAP-induced inflammatory activation while altering glycolysis- and lactate-related signaling markers in infected macrophages, and unraveled the predicted molecular mechanism by which MGO suppresses inflammation and modulates oxidative damage.

Heba R Alrefaey, S. Naser · 0 citations

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