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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Heidi M. Haikala

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2 papers indexed here

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Open access Aug 2026

PARP inhibition enhances the antitumor activity of HER3-DXd in non-small cell lung cancer

It is suggested that combining HER3-DXd with PARP inhibitors with a significant synergy is observed with PARP inhibitors, effective in both EGFR- and KRAS-mutated NSCLC models, effectively targeting diverse NSCLC subtypes.

Linh Lin, Narges Moradi, I. Lähdeniemi et al. · 0 citations
Open access Aug 2026

BAF perturbation heightens cancer cell dependence on CDK12-driven transcription elongation by RNA polymerase II

CDK12 facilitates transcriptional elongation and processivity by RNA polymerase II (Pol II). Although it has emerged as a promising actor and target in cancer, better understanding of CDK12 gene transcription control could inform the design of novel anti-cancer strategies. Here, we identify a co-dependency between CDK1...

Monika Mačáková, Cassidy Danyko, Stefan Oberlin et al. · 0 citations

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