H2-O deficiency in B cells or dendritic cells drives retrovirus-neutralizing antibody responses
ABSTRACT Major histocompatibility complex class II (MHC II)-restricted antigen presentation is central to CD4+ T-cell activation and the generation of high-affinity, class-switched antibody (Ab) responses. Peptide loading of MHC II in endosomal compartments is modulated by the functional interplay of two nonclassical M...