Author

Helena Mannochio-Russo

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Open access Aug 2026

Emerging Microbial Lipid Shifts in a Multistage Simulated Gut Inoculated with Human Fecal Microbiota.

Food residues that bypass human digestion are further digested by gut microbes, leading to the production of diverse metabolites, including lipids. To investigate how lipids in our intestine are affected during this transition, we used a colon simulator with four distinct vessels (V1-V4) that mimic the proximal to dist...

I. Tamanna, Katja Salonen, Helena Mannochio-Russo et al. · Journal of Proteome Research · 0 citations

Open access Sep 2026

Gut microbiome and metabolite profiles are associated with subsequent histologic MASH in a longitudinal mouse model

ABSTRACT Detecting metabolic dysfunction-associated steatohepatitis (MASH) before fibrosis develops remains a major challenge. We used a longitudinal streptozotocin/high-fat diet (STAM/HFD) mouse model to identify microbial and metabolic features that emerge before histological MASH onset. Integrative 16S rRNA and unta...

Stephany Flores Ramos, Kelly A. Fogelson, V. Muti et al. · mSystems · 0 citations