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Author

Henan Zhou

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Aug 2026

7,8-dihydroxyflavone exerts neuroprotective effects against traumatic brain injury in mice via the TrkB-dependent anti-ferroptotic ERK/CREB/GPX4 pathway.

Traumatic brain injury (TBI) triggers severe secondary brain damage with ferroptosis as a key driver. 7,8-dihydroxyflavone (7,8-DHF), a selective TrkB agonist, has known neuroprotective properties, yet its regulatory role in TBI-related ferroptosis remains unclear. This study aimed to explore whether 7,8-DHF alleviates...

Jian Song, Gu-Zheng Xu, Li Wang et al. · 0 citations

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