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Author

Heng Tang

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Open access Sep 2026

TET1 loss promotes malignant phenotypes in HeLa cells and is associated with altered PTEN–PI3K/AKT/mTOR signaling

Reduced TET1 expression was observed in SCC-restricted public cohorts, while TET1 depletion promoted malignant phenotypes in HeLa cells, which identifies a candidate signaling association that warrants validation through rescue experiments and locus-specific epigenetic studies.

Yang Liu, Lu-Jia Liu, Lu-Sheng Wang et al. · 0 citations
Open access Aug 2026

Quercetin protects HTR-8/SVneo human trophoblast cells against oxidative stress injury via activating EGFR/PI3K/AKT-NRF2/HO-1 signaling axis

Investigating whether quercetin alleviates H2O2-induced oxidative damage in HTR-8/SVneo trophoblasts via regulating the EGFR/PI3K/AKT-NRF2/HO-1 axis provided a novel mechanism and potential intervention for adverse pregnancy outcomes.

Lu-Jia Liu, Zhixian Ding, Yi-Na Wu et al. · 0 citations
Aug 2026

A halotolerant marine β-glucosidase from Celeribacter halophilus for efficient bioconversion of soybean isoflavone glycosides to bioactive aglycones.

High catalytic efficiency in hydrolyzing glycosidic bonds and substantial increases in the yields of bioactive daidzein and genistein are highlighted, highlighting ChaBGL's significant potential for diverse industrial applications, particularly in the nutritional, veterinary, and pharmaceutical sectors.

Fei Chang, Yi-Le Wang, Jian-Ping Ou et al. · 0 citations

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