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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Henrique Izaias Marcelo

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Open access Sep 2026

Interpretable Multiomics Machine Learning Identifies GSDMB-Associated Epigenetic Repression and Reduced Immune Activity in Metastatic Colorectal Cancer

Background Colorectal cancer (CRC) is a major cause of cancer-related mortality, with distant metastasis strongly associated with poor clinical outcomes. Integrating transcriptomic and epigenomic data through machine learning may improve the molecular characterization of metastatic CRC. Methods We analyzed 518 primary...

Matheus da Silveira Costa, Henrique Izaias Marcelo, Gabriel Albanese Kafouri et al. · 0 citations

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