Review
Open access
Sep 2026
Targeting the Siglec/sialic-acid axis in glioblastoma: Glycome-mediated immune evasion and emerging therapeutic platforms
Abstract Despite encouraging advances in cancer immunotherapy, several malignancies leverage resistance pathways to escape the effects of treatment. Abnormal cell signaling and cytokine secretion modulated by cancer cells promote a tumor microenvironment (TME), wherein the efficacy of infiltrating immune cells is dimin...
David Lee, William ElNemer, O. Selim et al.
· Neuro-Oncology Advances · 0 citations