Open access
Aug 2026
The S1B-Targeting PEDV Neutralizing Antibody C62 Prematurely Activates S-trimer and Mimics Receptor Function
The structure of PEDV HNXX-strain spike domain B (S1B) is determined and a strain-specific vulnerable site on the PEDV S-trimer is identified, providing insight into how cell-surface membrane fusion activity may influence viral entry pathway selection and antibody neutralization efficacy.
Jian-Bo Liu, Sheng Wang, Zi-Mu Li et al.
· bioRxiv · 0 citations