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Jul 2026

Conserved moonlighting protein pyruvate dehydrogenase induces robust protection against Staphylococcus aureus infection 2248909

It is shown that immunization with PDHC confers robust protection against lethal S. aureus strains, including MRSA, even in previously exposed hosts, as well as protecting against diverse S. aureus strains in multiple murine models.

Jiandong Huang, Xiaolei Wang, Y. Dou et al. · 0 citations