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Author

Hirohisa Watanabe

2 papers indexed here

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Open access Oct 2026

Tegmental atrophy in isolated REM sleep behaviour disorder: ex vivo MRI–informed in vivo imaging

Isolated rapid eye movement (REM) sleep behaviour disorder (iRBD) is an early-stage synucleinopathy characterized by brainstem pathology. In rodents, the pontine tegmentum contains a REM sleep centre, the sublaterodorsal nucleus, which expresses corticotropin-releasing hormone binding protein (CRHBP). While the invol...

Masakazu Hirose, Kenji Yoshinaga, Yoshifumi Mori et al. · 0 citations
Review Open access Oct 2026

Multimodal neuroimaging in dementia and neurodegenerative disorders: complementary roles of clinically available nuclear medicine and MRI in the era of disease-modifying therapies.

The introduction of anti-amyloid-β antibody therapies has fundamentally changed the clinical landscape of dementia, shifting the role of neuroimaging from diagnosis toward therapeutic decision-making. Amyloid positron emission tomography (PET) has become essential for confirming amyloid pathology and determining treatm...

Y. Inui, Hajime Takechi, Hirohisa Watanabe et al. · 0 citations

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