Hiroki Aoyama

Evaluation of subacute toxicity of highly bioavailable curcuRouge® formulation by a repeated dose 28-day oral exposure toxicology study in sprague dawley rats with safety assessment

CurcuRouge®, a high-bioavailability amorphous curcumin formulation, was orally administered to male and female Sprague–Dawley (Slc) rats at a dose of 750 mg/kg/day (equivalent to 300 mg/kg/day of curcumin) for 28 days to evaluate its subacute toxicity. Clinical signs, body weight, urinalysis, hematological and biochemi...