Open access
Aug 2026
Unique CD8+ T Cell Populations Expand during ART and Predict Delayed HIV-1 Rebound
A dynamic CD8+ T cell state continuum is identified as a central determinant of HIV-1 rebound, even in the absence of antigen-specificity, where ART establishes a predictive poised naïve state that can be further leveraged by vaccination to enhance protective stem-like memory responses.
Jie Wang, Gautam Kundu, P. Ehrenberg et al.
· bioRxiv · 0 citations