Examination of Antigen-Specific B Cell Responses to Red Blood Cell Transfusion.
This work will examine the development and use of B cell tetramers for the purpose of studying antigen-specific B cell responses following RBC transfusion.
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This work will examine the development and use of B cell tetramers for the purpose of studying antigen-specific B cell responses following RBC transfusion.
Clinical apheresis waste is used to generate a single-center biobank of high-quality, research-grade CD34+ HSPCs from patients with sickle cell disease and beta-thalassemia, addressing a recognized gap in the hemoglobinopathy pipeline.
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