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Author

Hitomi Matsuzaki

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Open access Sep 2026

Two distinct domains in mouse IG-DMR of the Dlk1–Dio3 locus confer imprinted DNA methylation in transgenic mice

Faithful maintenance of allele-specific methylation at imprinting control regions (ICR) is essential for genomic imprinting. Using transgenic mice (TgM), we investigated sequence requirements for paternal methylation acquisition and maternal hypomethylation maintenance during early embryogenesis. We previously show...

Mizuki Morihashi, Hitomi Matsuzaki, Teruhito Ishihara et al. · 0 citations

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