Role of yeast MIG1 gene in glycolysis, mitochondrial bioenergetics, and glycogen and trehalose biosynthesis in response to DNA damage
Background: In eukaryotic cells, under certain stress conditions, the diversion of carbohydrate flux, either downstream toward tricarboxylic acid (TCA) cycle or upstream toward the hexosamine biosynthesis and pentose phosphate pathways, is governed by the activation of key regulatory genes and glycolytic enzymes. In Sa...