Hoang-Bach-Dat Le

Machine learning-derived Alzheimer’s disease dimensions: neuroanatomical, cognitive, clinical, functional, and genetic risk heterogeneity signatures

Alzheimer's disease (AD) is characterized by substantial clinical and biological heterogeneity, with diverse neuroanatomical, cognitive, clinical, functional, and genetic risk profiles that are poorly captured by current diagnostic frameworks. Identifying reproducible disease dimensions is critical for understanding di...