Polysaccharide-based dissolving microneedles reinforced by metal-polyphenol network: dual-enhancement of mechanical strength and photothermal-triggered drug penetration.
Skin diseases affect approximately 30%-70% of the global population and significantly reduce quality of life. Although polysaccharide-based dissolving microneedles (DMNs) are a minimally invasive transdermal delivery platform with strong clinical potential, their loose molecular packing and weak intermolecular interact...