Cocoa polyphenols in brain health: BDNF/CREB-mediated mechanisms in depression, cognition, and the gut–brain axis
Cocoa polyphenols have emerged as promising nutritional modulators of cerebral health through their multifaceted effects on neurobiological pathways. This review synthesizes contemporary clinical and preclinical evidence regarding their implications in depression, the gut-brain axis, neuroplasticity, and cognitive func...