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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Hong-Bin Ji

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Open access Oct 2026

Targeting PRPF19 suppresses lung cancer progression by abrogating cytokinesis and potentiating anti-tumor immunity

Lung cancer remains the leading cause of cancer-related mortality worldwide, highlighting the critical need to identify key oncogenic drivers and develop effective therapeutic strategies. Here, we demonstrate that pre-mRNA processing factor 19 (PRPF19) is significantly upregulated in lung cancer tissues and correla...

Shuai-Hu Li, Long-Fu Zhang, Tian Xu et al. · 0 citations
Oct 2026

Development of Potent and Selective EGFR-PROTACs Based on Macrocyclic Fourth-Generation EGFR Inhibitors

Epidermal growth factor receptor (EGFR) mutant-driven non-small cell lung cancer (NSCLC) frequently develops acquired resistance to third-generation tyrosine kinase inhibitors (TKIs), particularly through the EGFR C797S mutation. Existing EGFR-targeting proteolysis-targeting chimeras (PROTACs) remain limited by unfav...

Qin-Yang He, Yan Cheng, Qing Zhang et al. · 0 citations

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