The retina, as an extension of the central nervous system, shares a common embryological origin with the brain. In Alzheimer's disease (AD), studies of human tissue and animal models have revealed that hallmark AD pathologies, including amyloid-β (Aβ) deposits and pathological tau protein tangles, also appear in the re...
Xia-Yin Zhang, Dongli Zhuang, Chun-Ran Lai et al.· Progress in retinal and eye...· 0 citations
It is revealed that spatially defined immunometabolic remodeling—in which Trem2 + microglia are central—converges on sphingolipid metabolism as a druggable regulatory axis, with the TREM2‐SPTLC2 interface thus emerging as a new therapeutic opportunity for retinal neurodegenerative diseases.
Yun-Hong Shi, Jinpei Lin, Yi Wu et al.· iMeta· 0 citations
Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has been increasingly implicated in selected ocular diseases, although its causal relevance varies across disease entities. The retina and retinal pigment epithelium are biologically susceptible to ferroptosis-related injury becau...
Naiyuan Zhang, Huiqian Kong, Yu-Heng Liao et al.· International Journal of Oph...· 0 citations
This study successfully developed and validated an explainable RF-based machine learning model for the prediction of postoperative ACD in highly myopic cataract patients, which supports more reliable IOL power calculation and offers a practical tool for optimizing surgical planning in highly myopic eyes.
Yuyang Yang, Hao Cui, Jiajia Gao et al.· Frontiers in Cell and Develo...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
